Santa Maria in Brera was a church in Milan, in Lombardy in northern Italy. It was built by the Humiliati between 1180 and 1229, given a marble façade and Gothic portal by Giovanni di Balduccio in the fourteenth century, and deconsecrated and partly demolished under Napoleonic rule in the early nineteenth century. The Napoleonic rooms of the Pinacoteca di Brera occupy the upper floor of what was the nave.